Collagen Biostimulator in Singapore

Have you noticed that your skin has become less firm or radiant over time? If you are seeking a non-surgical solution that extends beyond topical skincare, collagen biostimulators may provide long-term improvement from within.

These treatments restore your skin’s strength and structure from within, yielding results that appear natural and last.

How Do Collagen Biostimulators Work?

Biostimulators such as poly-L-lactic acid (PLLA) and salmon-derived PDRN (polydeoxyribonucleotide) are collagen-stimulating treatments that gradually restore structure, elasticity, and vibrancy to the skin.

These injectables are not designed to provide instant volume like hyaluronic acid fillers. Instead, as collagen stimulators, they act as a scaffold beneath the skin, encouraging gradual collagen regeneration over weeks to months.

Treatment Process

During treatment, your doctor carefully injects the biostimulatory substance into targeted areas of the face, neck, or hands. The injections are administered in layers and patterns tailored to the specific area being treated, ensuring even distribution and optimal results.

Immediate Effects

Patients may experience mild swelling immediately after treatment due to the presence of the biostimulators and the added water content. However, this effect is temporary. The fundamental transformation happens over time.

Collagen Production

The biostimulator activates fibroblasts in the skin, prompting them to produce collagen. Over several weeks, this collagen rebuilds the skin’s structural matrix, thickening the dermis, improving elasticity, and evening out lines.

Long-Term Results

Collagen continues to regenerate for several months following treatment, with results becoming increasingly visible over time. Unlike temporary fillers, the improvements from biostimulators can last up to two years or more, depending on the type of product used and your skin’s natural ageing process.

What Do Collagen Biostimulators Treat?

Fine Lines and Wrinkles

Over time, repeated facial expressions and natural collagen breakdown lead to wrinkles, especially around the eyes, mouth, and forehead. Biostimulators work beneath the surface to reduce these lines, leaving the skin looking fresh and firm.

Loss of Facial Volume and Sagging Skin
One of the most noticeable signs of ageing is volume loss in the mid-face, which contributes to sagging. Biostimulators help rebuild collagen in deeper layers, restoring the skin’s foundational support and gradually lifting sagging areas over time.
Hollow Temples and Sunken Cheeks
When fat and collagen diminish in the temples or cheeks, the face can appear gaunt or tired. Collagen Biostimulators gently plump these areas by encouraging your body to replenish what time has taken away.
Nasolabial Folds and Marionette Lines
The deep lines that run from the nose to the mouth (nasolabial folds) or down from the mouth corners (marionette lines) can significantly age the face. Collagen production helps fill in these folds more naturally than traditional fillers, resulting in a softer and more balanced appearance.
Skin Laxity on the Face, Neck, and Hands
Loose, crepey skin around the jawline, neck, and hands can be challenging to treat. Biostimulators work gradually to tighten and thicken the skin, enhancing elasticity and firmness without the need for surgery.
Acne Scars and Uneven Skin Texture

Atrophic acne scars and rough texture are signs of damaged or thinned dermal layers. Collagen stimulation helps rebuild the skin’s structure, leading to more even skin over time.

Benefits of Biostimulators

Natural-Looking Results

Since collagen biostimulators gradually improve your skin from within, results appear subtle and natural.

Long-Lasting Effects

With proper maintenance, the collagen produced can last for years. Patients often need only yearly or bi-annual touch-ups after the initial series.

Minimal Downtime

Most patients go back to their daily activities immediately after the procedure. You may experience mild swelling or bruising, but these typically resolve within a few days.

Non-Surgical

Biostimulators are a non-invasive option that offers rejuvenation without incisions, anaesthesia, or significant recovery time.

How Are Collagen Biostimulators Different from Dermal Fillers?

Collagen Biostimulators and dermal fillers may seem similar, but they function differently and serve distinct purposes.

Aspect​​ Biostimulators​ Dermal Fillers

Mechanism of Action

Stimulate natural collagen production over time
Provide immediate volume using substances like hyaluronic acid

Longevity

Gradual results that can last 18–24 months or longer
Typically lasts 6–12 months, depending on the product and treatment area

Results

Subtle, progressive improvement with cumulative effects
Instant lift or volume, with results that may fade more quickly

Areas Treated

Ideal for mid-face, temples, jawline, and areas needing skin tightening
Ideal for lips, tear troughs, and areas requiring precise shaping or contouring

Who Are Ideal Candidates for Collagen Biostimulators?

Collagen Biostimulators suit individuals who:
However, collagen biostimulators may not be ideal for those expecting drastic changes or those with autoimmune disorders.

Step-By-Step Procedure

Consultation

During your initial visit, your doctor will assess your skin, review your goals, and explain how collagen biostimulators can be incorporated into your treatment plan.

Preparation​

No significant preparation is needed. Your doctor may advise you to avoid blood thinners, alcohol, and certain supplements to reduce the risk of bruising.

Treatment Process ​

Using fine needles or cannulas, the doctor injects the biostimulant into predetermined areas. The process usually takes 30-60 minutes.
Filler Icon

Massage​

Some products, such as PLLA, require firm massaging of the treated areas for several days post-treatment to distribute the product evenly.
Radio frequency

Post-Treatment Care

Your doctor may advise you to avoid strenuous activity, sun exposure, and facial treatments for a few days. Our team will arrange for follow-up appointments to assess your progress.

Better Skin with DermAlly

Collagen Biostimulators offer a subtle yet clinically effective approach to rejuvenation. At DermAlly, our dermatologists administer FDA-approved biostimulators with precision and care, restoring your skin’s structure and radiance from within.

Trust our medical team to support your skin’s long-term health and help you achieve natural, long-lasting results with minimal downtime.

Schedule a personalised consultation with our dermatologists to explore how collagen biostimulators can support your skin’s long-term rejuvenation goals.

Frequently Asked Questions

How long do biostimulators last?

Depending on the product used, results can last from 18 to 24 months or longer. Regular maintenance treatments can prolong the effects.

Are biostimulators better than dermal fillers?
Not necessarily, as they both serve different purposes; biostimulators are ideal for long-term collagen regeneration, while fillers provide immediate volume and contouring.
Do biostimulators work for acne scars?
Yes. By stimulating collagen, biostimulators can help improve pitted or atrophic acne scars and improve skin texture over time.
Is the procedure painful?
Most patients find the procedure tolerable. Doctors will use topical numbing cream or a local anaesthetic to minimise discomfort.
How many treatments are needed?
An initial series of 2–3 treatments spaced several weeks apart is typically recommended. After that, maintenance may be done once a year.
Are there any side effects?
Common side effects include swelling, redness, or bruising at injection sites. These usually resolve within a few days. Rare complications can consist of nodules or uneven texture, but these are preventable with proper technique.

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